Causes Of Osteoarthritis:
Can You Prevent Osteoarthritis?
Osteoarthritis is generally equated with a disease of wear and tear and old age.
Although it does usually accompany old age, researchers have found that the cartilage in a joint with osteoarthritis is chemically different than
a joint without the disease.
Researchers have also found that there are a series of events that lead to the development of
Osteoarthritis and that it isn’t associated with age alone. These events involve
the production, maintenance and breakdown of the cartilage in the joints. These joints are often
of the larger weight bearing joints of the body such as the knees and hips, which provide the majority of the cushion when we are doing any
weight bearing exercise such as walking, running etc.
Athletes who also perform repetitive motion exercise that is weight bearing on a joint, such as
rowing, will find that Osteoarthritis also will develop in the elbow and shoulder areas.
Researchers believe that there is a genetic component to the development of the disease but they
have not yet conclusively found that link. They have found that there is a higher correlation in
the development of this arthritis between parent and child or siblings than between husband and wife.
In a study completed in 2000 a gene was identified which was thought to regulate the production of
a chemical, pyrophosphate, which inhibits the formation of mineral deposits in the joints. They
theorize that this chemical may protect the cartilage in the joints. About 60% of patients with
Osteoarthritis were found to have mineral deposits in their joints.
People with this disease also have muscle weakness, especially in the quadriceps
muscles. These are the four large muscles in the front of the thigh that enable the body to
extend the knee. Researchers understand that the arthritis creates a painful situation and
patients may not exercise, therefore decreasing their muscle strength. However, they also
theorize that the weakness, especially in the quadriceps, pre-dates the development and actually causes the degeneration of the
joint. The stronger the muscle mass the better able the body is to protect the joints.
Anatomical reasons also are considered to be involved in the development of this
arthritis. Research has found that people who are ‘bow-legged’ or ‘knock-kneed’ are more likely
to develop progressive osteoarthritis in the knees. Other research has found that some people are
born with joints that don’t meet smoothly and cartilage that isn’t formed correctly.
Injuries also play a large part in the joint changes that lead to
Osteoarthritis. People with knee injuries early in life were 16% more likely to
develop arthritis in the affected knee than those without an injury. Other medical conditions
have also been found to play a part in the cause of Osteoarthritis. Hemophiliacs have the
potential to bleed into the joints causing damage to the cartilage. People with chronic gout and
pseudogout have mineral deposits in the joints from the crystals that cause the gout. People with
rheumatoid arthritis already have joint damaging inflammation that injures to the cartilage.
Although the causes of Osteoarthritis have not been completely defined people can use the knowledge that researchers now have to
potentially delay the onset or stop the development of this painful disease.
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